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Inhibition of HRP-tagged Vibrio cholerae cholera enterotoxin subunit B5 binding to GM1 coated plates using GM1os-beta-NAc-propargyl
Assay data:2 Active, 2 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antibacterial activity against Vibrio cholerae A1552 El Tor assessed as bacterial growth inhibition incubated for 18 to 20 hrs by broth microdilution method
Assay data:3 Tested
SummaryPubMed Citation
Inhibition of Vibrio cholerae gamma carbonic anhydrase preincubated with enzyme for 15 mins by phenol red-based stopped-flow CO2 hydration assay
Assay data:18 Active, 1 Activity ≤ 1 µM, 18 Tested
Inhibition of Vibrio cholerae beta carbonic anhydrase preincubated with enzyme for 15 mins by phenol red-based stopped-flow CO2 hydration assay
Assay data:19 Active, 11 Activity ≤ 1 µM, 19 Tested
Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated with enzyme for 15 mins by phenol red-based stopped-flow CO2 hydration assay
Assay data:19 Active, 19 Activity ≤ 1 µM, 19 Tested
Inhibition of Vibrio cholerae gamma carbonic anhydrase pre-incubated for 15 mins prior to testing by phenol red-based stopped-flow CO2 hydration assay
Assay data:10 Active, 10 Activity ≤ 1 µM, 10 Tested
Inhibition of Vibrio cholerae alpha carbonic anhydrase pre-incubated for 15 mins prior to testing by phenol red-based stopped-flow CO2 hydration assay
Inhibition of Vibrio cholerae beta carbonic anhydrase pre-incubated for 15 mins prior to testing by phenol red-based stopped-flow CO2 hydration assay
Assay data:28 Active, 26 Activity ≤ 1 µM, 28 Tested
Inhibition of Vibrio cholerae gamma carbonic anhydrase incubated for 30 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay
Assay data:25 Active, 15 Activity ≤ 1 µM, 25 Tested
Inhibition of Vibrio cholerae beta carbonic anhydrase incubated for 30 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay
Assay data:7 Active, 2 Activity ≤ 1 µM, 25 Tested
Inhibition of Vibrio cholerae alpha carbonic anhydrase incubated for 30 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay
Assay data:25 Active, 24 Activity ≤ 1 µM, 25 Tested
Inhibition of Vibrio cholerae MetAp1a by Morrison method
Assay data:35 Active, 25 Activity ≤ 1 µM, 36 Tested
Inhibition of cholera toxin in human intestinal organoids assessed as reduction in oganoids swelling using cholera toxin pre-incubated with compound for 4 hrs before organoid stimulation with cholera toxin by calcein AM staining based confocal microscopy
Inhibition of Vibrio cholerae beta carbonic anhydrase incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay
Assay data:8 Active, 8 Activity ≤ 1 µM, 8 Tested
Inhibition of Vibrio cholerae alpha carbonic anhydrase incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay
Antibiofilm activity against Vibrio cholerae assessed as inhibition of biofilm dispersion
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Antibiofilm activity against Vibrio cholerae
Inhibition of Vibrio cholerae beta-CA incubated for 15 mins by stopped-flow CO2 hydration assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of Vibrio cholerae beta carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay
Assay data:10 Active, 10 Tested
Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay
Assay data:10 Active, 2 Activity ≤ 1 µM, 10 Tested
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